Imikhiqizo
I-Uracil Pyrimidine-2,4(1H,3H)-dione
Synonym: Uracil
I-Chemical Property ye-Uracil
● Ukubukeka/Umbala:impushana emhlophe
● Umfutho Wokuhwamuka:2.27E-08mmHg ku-25°C
● Indawo Encibilika:>300 °C(lit.)
● I-Refractive Index: 1.501
● Indawo yokubilisa:440.5°C ku-760 mmHg
● PKA:9.45(ku-25℃)
● I-Flash Point:220.2oC
● I-PSA: 65.72000
● Ukuminyana:1.322 g/cm3
● I-LogP:-0.93680
● Ukushisa Kwesitoreji.:+15C ukuya ku-+30C
● Ukunyibilika.:I-Aqueous Acid (Kancane), i-DMSO (Kancane, Ishisiwe, I-Sonicated), i-Methanol (Kancane,
● Ukunyibilika Kwamanzi.:INQABUKA EMANZINI OKUSHISAYO
● I-XLogP3:-1.1
● Isibalo Somnikeli Webhondi Ye-Hydrogen:2
● Isibalo Sokwamukela Ibhondi Ye-Hydrogen:2
● I-Rotatable Bond Count:0
● IMisa Langempela:112.027277375
● Isibalo se-athomu esindayo:8
● Ukuba yinkimbinkimbi:161
Ubumsulwa/Ikhwalithi
99%, *idatha evela kubahlinzeki abangavuthiwe
I-Uracil *idatha evela kubahlinzeki be-reagent
Ulwazi Oluphephile
● Ama-Pictogram:
Xi
● Amakhodi Wengozi:Xi
● Izitatimende Zokuphepha:22-24/25
Iwusizo
● Amakilasi Amakhemikhali: Ama-Biological Agents -> Ama-Nucleic Acid kanye Nokuphuma Kwawo
● I-Canonical AMAMAMOTHO: C1=CNC(=O)NC1=O
● Izivivinyo Zomtholampilo Zakamuva: Ucwaningo lwe-Uracil Topical Cream (UTC) lwe-Prevention of Hand-Foot Syndrome engu-0.1%
● Izivivinyo Zomtholampilo Zakamuva ze-EU: Onderzoek naar de farmacokinetiek van uracil na orale toediening bij pati?nten met colorectaal carcinoom.
● Izilingo Zomtholampilo Zakamuva ze-NIPH: Ukuhlolwa kwesigaba II se-uracil ointment yokuvimbela i-capecitabine eyenziwe nge-hand-foot syndrome (HFS):.
● Ukusetshenziswa: Ngocwaningo lwamakhemikhali ezinto eziphilayo, ukuhlanganiswa kwezidakamizwa;isetshenziswa njengezinqamuli zemithi, iphinde isetshenziswe ekuhlanganiseni okuphilayo Isisekelo se-nitrogenous kuma-nucleosides e-RNA.i-antineoplastic Ocwaningweni lwe-biochemical.I-Uracil (i-Lamivudine EP Ukungcola F) iyisisekelo se-nitrogen ku-RNA nucleosides.
● Incazelo: I-Uracil iyisisekelo se-pyrimidine kanye nengxenye eyisisekelo ye-RNA lapho ibophezela khona ku-adenine ngamabhondi e-hydrogen.Iguqulwa ibe yi-nucleoside uridine ngokufakwa kwe-ribose moiety, bese i-nucleotide uridine monophosphate ngokufaka iqembu le-phosphate.
