Imikhiqizo
Methylparaben; Cas No.: 99-76-3
Amanyanjana: 4-hydroxybenzoic acid methyl ester; methyl p-hydroxybenzoate; methyl-4-hydroxybenzoate; methylparaben; methylparaben; methylparaben; methylparaben; i-sodium usawoti; NIPAGIN
Impahla yamakhemikhali ye-methylparaben
● Ukubukeka / Umbala: I-White Crystalline Powder
● Ingcindezi ye-Vapor: 3.65E-05mmhg ngo-25 ° C
● Iphuzu elincibilikayo: 125-128 ° C (lit.)
● Inkomba ye-Ref Resuac: 1.4447 (Linganisa)
● Iphuzu elibilayo: 265.5 ° C ku-760 mmhg
●: PKA 8.15 (H2O, T = 20.0) (Okungaqinisekile)
● Iphuzu le-Flash: 116.4 ° C
● Psa:46.53000
● Hlensity: 1.209 g / cm3
● logp: 1.17880
● Isitoreji Temp.:0-6enduc
● I-Solubity.isethanol: Soluble0.1m, Sula, Ungenamibala
● Amanzi e-solubility.:lyly incaluble emanzini.
● xLogp3: 2
● I-Hydrogen Bond Donor Count: 1
● Ukubalwa Kwama-Hydrogen Bond kwamukelwa: 3
● I-rotatable Bond Count: 2
● Isisindo esiqondile: 152.047344113
● Isibalo se-athomu esindayo: 11
● Ukuba yinkimbinkimbi: 136
Imininingwane Ephelile
● pictograph (s):
I-XI,
I-XN
● Amakhodi Anobungozi: XI, XN
● Izitatimende: 36/37/18-20 / 21/36-36
● Izitatimende Zokuphepha: 26-36-24 / 25-39
-Sizayo
Amakilasi Amakhemikhali:Okunye ukusetshenziswa -> ukulondolozwa
Ukumamatheka kwe-canonical:Coc (= o) c1 = cc = c (c = c1) o
Sebenzisa:I-methylparaben i-ester ye-methyl alcohol ne-p-hydroxybenzoic acid, i-ejenti ye-bacteroxiostatic, i-ejenti ye-bacteriostatic kanye nokulondolozwa okwengeziwe kuma-vasoconstricters ngaphambi kokukhishwa kwalolu hlelo kusuka kuma-vasocontivel anents okuholwa yi-avel anesthetic solutions.siminar imikhiqizo ekhiqizwa ngokukhiqizwa okufanayo Izindlela, njengo-Ethyl P-Hydroxybenzoate (Paraben B) kanye nePropelc P-Hydroxybenzoate (Nepalese C), nazo zibulala amagciwane.Imikhiqizo ecasulayo esikhunjeni. AmaParabhun angenye yeqembu elisetshenziswa kakhulu lezimbozo ezihlotshisweni, ezenzakalisayo kanye nezimboni zokudla. AmaParabhuni ahlinzeka ngomsebenzi we-bacteristatic kanye nomsebenzi ophikisana nenani elihlukile lezinto eziphilayo, futhi abhekwa njengephephile ukuze asetshenziswe kwezimonyo, ikakhulukazi ekukhanyeni kwamandla abo okuzwela okuphansi. Ukuhlolwa kwezivikelo zokusetshenziswa kumalungiselelo wokuhlelwa kwezimonyo kuhlu amapharabheli phakathi kokuzwela okuncane. Uhla lokugxila olusetshenziswa kuma-cosmetics luyahlukahluka phakathi kuka-0.03 namaphesenti angama-0,30, kuya ngemibandela yokusebenzisa kanye nomkhiqizo lapho iParaben ingezwe khona i-preservatives ethandwa kakhulu yemikhiqizo yobuhle nezinto zokudla. Ngokusho komtapo wezincwadi wezokwelapha, isithako senzeka ngokwemvelo ezithelo ezimbalwa - njenge-blueberries - yize kungakhiwa futhi nge-creams and the moisturizer kuma-realers kanye nezisekelo futhi kusiza le mikhiqizo iqhubeke nokusebenza kwabo. URabach uthi kunama-chock-agcwele izakhiwo ezilwa ne-fungal kanye ne-antibacterial, ezisebenza izimangaliso zokunweba impilo eshalofini ye-skincare, izinwele zezinwele, kanye nemikhiqizo yezimonyo.
I-methylparaben yi-ejenti ye-antimicrobial okuyimpuphu emhlophe egeleza mahhala. Iyasebenza ngokuphikisana nemvubelo nokubumba ngaphezulu kobubanzi be-PH. Bheka amapharabhu. I-methyl 4-hydroxybenzoate isetshenziswa njenge-ejenti elwa ne-fungal. Kusetshenziswa futhi njengokulondolozwa kokudla, iziphuzo kanye nezimonyo. Isebenza njenge-inhibetor yokukhula kwezikhunta kanye namagciwane amancane aphansi kanye nemoto yesisombululo se-ophthalmic.
Isingeniso Esinemininingwane
I-methylparaben iyindlela yokugcina esetshenziswa kakhulu embonini yezimonyo kanye neyomuntu siqu. Kuyilungu lomndeni wakwaParaben, okubandakanya ezinye izinto zokugcina ezinjenge-ethylPapareben, i-proplparpaneben, ne-butylpareben.ERE ngamaphuzu asemqoka nge-methylparaben:
Ukulondolozwa: I-methylparaben ingezwa kwizimonyo kanye nemikhiqizo yokunakekelwa komuntu ukuvikela ukukhula nokwanda kwama-microorganisms afana namagciwane kanye nesikhunta. Kuyasiza ukunweba impilo yeshelufu yale mikhiqizo futhi igcine ikhwalithi yabo nokuphepha kwabo.
Ukuphepha:I-methylparaben ifundelwe kabanzi futhi yathathwa njengephephile ukuthi isetshenziswe kwizimonyo kanye nemikhiqizo yokunakekelwa komuntu ngezidakamizwa eziphathelene ne-US Food and Drug Administration (i-SCCS), kanye nephaneli yesitholiso sokubukeza (CIR).
Ukusetshenziswa Okubanzi:I-methylparaben ingatholakala emikhiqizweni ehlukahlukene, kufaka phakathi okhilimu, ama-lotion, ama-shampoos, ama-conditioners, ukwakheka, ama-deodorants kanye nama-sunscreens. Kusetshenziswa kabanzi ngenxa yokusebenza kwayo, ukuqina, kanye nokuhambisana nokwakheka kwezimonyo eziningi.
Amanye amaParabhu: I-methylparaben ivame ukusetshenziselwa ukuhlanganiswa namanye amapharabheli (njenge-ethylparaben, i-proplparaben, ne-butylpapaben) ukuhlinzeka nge-spectrum ebanzi yokuvikelwa kwe-antimicrobial.
Okunye ukulondolozwa:Eminyakeni yamuva nje, kukhuphuke kakhulu kwesidingo sabathengi sezindlela zokulondolozwa. Njengempendulo, ezinye izinkampani zezimonyo seziqalile ukusebenzisa ezinye izindlela zokugcina noma zokukhetha zokwakhiwa kwamahhala. Kodwa-ke, i-methylparaben ihlala isetshenziswa kabanzi futhi ivunyelwe embonini embonini.
Kubalulekile ukuqaphela ukuthi ngenkathi kufundwe kakhulu futhi kuthathwe kuphephile ukusetshenziswa, abanye abantu bangathola ukuzwela noma ukusabela komzimba kuwo, njenganoma yisiphi esinye isithako. Uma unezinto ezikhathazayo noma imibuzo ethile mayelana nezithako zezimonyo, kungcono ukubonisana nodokotela wesikhumba noma ochwepheshe bezokunakekelwa kwempilo.
Isicelo
I-methylparaben isetshenziswa ngokuyinhloko njengendawo yokugcina ekunakekelweni komuntu siqu, izimonyo, nemikhiqizo yezemithi. Injongo yayo eyinhloko ukuvikela ukukhula kwamagciwane, imvubelo, nokubumba, ngaleyo ndlela kunwebe impilo yeshalofu nokuqinisekisa ukuphepha kwale mikhiqizo. Nazi ezinye izinhlelo ezijwayelekile ze-methylparaben:
Imikhiqizo ye-Skincare:I-methylparaben ingatholakala kuma-moisturizeds, abahlanza, imaski yobuso, ama-toners, kanye neminye imikhiqizo ye-skincare ukuze ilondoloze ikhwalithi yabo futhi ivikele ukungcoliswa kwe-microbial.
Imikhiqizo Yezinwele:I-methylparaben isetshenziswa kuma-shampoos, ama-conditioners, imaski yezinwele, kanye nemikhiqizo yezitayela ukugcina ifomula yabo futhi ivimbela ukukhula kwama-microorganisms.
Imikhiqizo Yokunakekelwa Komzimba:I-methylparaben ivame ukungezwa ku-motion yomzimba, ukugeza umzimba, ama-deodorants, nezinye izinto zokunakekela umuntu ukuvikela ukuposa nokugcina ukuqina komkhiqizo.
Imikhiqizo Ye-Makeup:I-methylparaben isetshenziswa kakhulu ezinhlotsheni ezahlukahlukene zezimonyo, kufaka phakathi izisekelo, amapopi, ama-eyeshadows, ama-bloshwas, nezindebe, ukuvikela ukukhula kwamagciwane kanye nesikhunta.
Imikhiqizo yezemithi:I-methylparaben ingaba khona ekumisweni kokumiswa komlomo, okhilimu, ama-ointrements, kanye nokunye ukwakheka kwemithi njengendawo yokugcina yokuqinisekisa ukuphepha kwazo nokuvimbela ukungcoliswa kwabo.
Kubalulekile ukuqaphela ukuthi ukusetshenziswa kwe-methylparaben emikhiqizweni kulawulwa yiziphathimandla ezinjenge-FDA (e-United States) kanye neKhomishini yaseYurophu e-EU. Lezi zinhlaka zibeka imikhawulo yokuhlushwa ekusetshenzisweni kwe-methylparaben kanye nezinye izinto zokugcina ukuqinisekisa ukuphepha komkhiqizo.
