Imikhiqizo
Dl-4-chlorophenyllycine; Case No.: 6212-33-5
Amanyanjana: 6212-33-5; 2-amino-2- (4-chlorophenyl) acetic acid; DL-4-Chlorophenyllycine; I-DL-2- (chlorophenyl) glycine; Amino (chlorophenyl) glycine; Amino (chlorophenyl) I-acetic acid; i-acid; 4-chlorophenylglycine; dl- (4-chlorophenyl) glycine; .lpha.-Amino-4-Chloro-; l-4-chlorophe 9lycine; 4-chloro-dl-phenyllycine; mfcd037001467; mfcd03839815; h -dl-phg (4-cl) -h; methyln-carbamoylmaleamate; rm2jw43tga; 2- (p-chlorophenyga; 2- (p-chlorophenyl) glycine; DL-2- (4-ChlorofenLel ); #; BCP25773; BBL022163; BDBM50179705; I-P-Chloro-Alpha-Aminopheyylacetic acid; APK130690; i-acid; 7l-304s; AB02094; AB15770; AB16238; AB88361; A-AMIno-4-Chloro-; I-HY-W00222377; I-DL-AL0022337; I-acid; sy017756; Sy034115; Sy034129; AM20060793; ft-0625923; ft-06453847; ft-06253847; (Tlc); Q-102258; F2147-0645; I-Z317024646;
Impahla yamakhemikhali ye-DL-4-Chlorophenyllycine
● Ukubukeka / umbala: mhlophe ukukhanyisa i-crystal powder ephuzi
● Ingcindezi ye-Vapor: 7.45E-05MmHG ngo-25 ° C
● Iphuzu elincibilikayo: 220-230 ° C
● Inkomba evulekayo: 1.603
● Iphuzu elibilayo: 328.8 ° C ku-760 mmhg
● I-PKA: 1.81 ± 0.10 (Ebikezelwe)
● Iphuzu le-Flash: 152.7 ° C
● Psa:I-63.32000
● Hlensity: 1.392 g / cm3
● logp: 2.12470
● Isitoreji Temp.:Keep endaweni emnyama, umkhathi we-inert, lokushisa legumbi
● I-Solubity.:SOLUble in 0.1mol / l naoh (cishe sobala).
● xLogp3: -1.1
● I-Hydrogen Bond Donor Count: 2
● Ukubalwa Kwama-Hydrogen Bond kwamukelwa: 3
● I-rotatable Bond Count: 2
● Isisindo esiqondile: 185.0243562
● Isibalo se-athomu esindayo: 12
● Ukunkimbanisa: 166
Imininingwane Ephelile
● pictograph (s):
I-XN
● Amakhodi Anobungozi: XN
● Izitatimende: 22-36 / 37/38
● Izitatimende zokuphepha: 26-36
-Sizayo
Ukumamatheka kwe-canonical:C1 = CC (= CC = C1C (C (= o) o) n) cl
Sebenzisa:Kuyinto ebalulekile ebonakalayo ebonakalayo kanye ne-Intermediate esetshenziswa ekuhlolweni kwe-organic, amakhambi, ama-agrochemicals kanye ne-dyestuff.
Isingeniso Esinemininingwane
2-Amino-2- (4-Chlorophenyl) I-Acetic Acid yaziwa nangokuthi igama lawo lamakhemikhali, 4-Chloro-Alpha-AminobenzeeceActic acid. Kuyimpuphu emhlophe ye-crystalline enendlela yamangqamuzana ye-c8h8clno2 kanye nesisindo samangqamuzana esingu-185.61 g / mol.
Nayi eminye imininingwane eyengeziwe mayelana no-2-amino-2- (4-chlorophenyl) acetic acid:
Synthesis:Le comporc ingahlelwa ngezindlela ezahlukahlukene, kufaka phakathi ukusabela kwe-4-chlororophetonenone nge-glycine phambi kwe-agent encishisiwe efana ne-sodium borohydride, noma ngokusabela kwe-4-chlorofenayl Bromide nge-sodium glyciate.
Izakhiwo ezingokomzimba nezamakhemikhali:
Iphuzu le-1.meling: Iphuzu lokuncibilika le-2-amino-2- (4-chlorophenyl) acetic acid ngokuvamile cishe ngo-135-140 ° C.
2.Salicity: Kuncibilika kancane emanzini, kepha kuncibilika kahle ku-organic solvents efana ne-ethanol ne-methanol.
U-3.ph: Esikhani esinamanzi, le mpikiswano ibuthakathaka i-acid nge-pH ezungeze i-5-6.
Izakhiwo zebhayoloji:
Imisebenzi ye-1.Parmacological: Yize kunolwazi olulinganiselwe olutholakala emisebenzini yakwa-2-amino-2- (4-chlorophenyl) acetic acid, ezinye izifundo ziphakamisa ukuthi zingaba nezici ezingaba khona zokuvuvukala kanye ne-analgesic.
2.Metabolism: Isiphetho se-metabolic sale nhlanganisela kubantu asibhalwa kahle. Kodwa-ke, kulindeleke ukuthi ihlukaniswe nge-enzymatic kanye nokuqedwa komzimba.
Ukucatshangelwa Kwezokuphepha:
I-1.Wino 2-Amino-2- (4-Clorophenyl) Ngokuvamile i-acetic acid ibonwa njengenobuthi obuphansi, kunconywa ukuyiphatha ngokucophelela futhi ilandele noma isebenza nale nhlanganisela.
2.Kubalulekile ukugqoka imishini yokuvikela, efana namagilavu kanye nama-goggles, futhi uqinisekise umoya omncane lapho usebenza nale nto.
I-3.Always ibhekisa kumashidi wedatha yezokuphepha (SDS) futhi abhekane nemihlahlandlela yezokuphepha efanele kanye nemigomo lapho ephatha futhi esebenzisa le nhlanganisela.
Khumbula, imininingwane enikezwe lapha i-General Overview futhi akufanele ibhekwe njengendawo ephelele noma eqeda amandla. Ngezinhlelo zokusebenza noma izinhloso ezithile, kuhlale kunconywa ukubheka izincwadi ezikhethekile noma imithombo ethembekile yemininingwane enemininingwane.
Isicelo
2-Amino-2- (4-Chlorophenyl) I-Acetic Acid, eyaziwa nangokuthi 4-Chloro-Alpha-Aminobenzeetic acid, inezinhlelo zokusebenza ezingaba khona emasimini ahlukahlukene. Nazi ezinye izinhlelo zokusebenza ezingenzeka:
Imboni Yezemithi:
1.Ukuhlanganiswa kwezidakamizwa: Ingasetshenziswa njengebhulokhi yokwakha noma eliphakathi nendawo ekuhlanganiseni kwamakhompiyutha emithi afana ne-analgesics, izidakamizwa ezilwa nokuvuvukala, noma ama-anti-bacterial agents.
2.Ukuthuthukiswa kwe-Prodrug: 2-amino-2- (4-chlorophenyl) kungenzeka i-acetic acid acid ingasetshenziselwa ukuthuthukisa ama-prodrugs, okuyizidakamizwa ezingasebenzi noma ezingasebenzi ezikhuthaziwe ziguqulwe zibe yifomu elisebenzayo emzimbeni. Lokhu kungasiza ukuthuthukisa ukusebenza kwezidakamizwa, ama-bioavailability, noma kunciphise imiphumela emibi.
Ucwaningo lwamakhemikhali:
1.Ukuhlanganiswa kwe-organic: I-Compound ingasetshenziswa elabhoratri lokuhlekisa nge-organic synthesis, ikakhulukazi ekuhlanganiseni kwezinto eziyinkimbinkimbi ze-organic.
2.I-Ligand Synthesis: Kungasetshenziswa ukulungiswa kwama-Ligands ukuxhumanisa amakhemikhali noma ama-carlysts ngokuphendula okuhlukahlukene kwamakhemikhali.
Imboni Yezolimo:
1.I-Pesticide Development: 2-amino-2- (4-chlorophenyl) ingasetshenziswa ukuhlanganisa ama-pesticides amasha noma ama-herbicides anikela ngempumelelo noma umthelela othuthukisiwe wezemvelo.
Ucwaningo Nentuthuko:
1.Ucwaningo lwamakhemikhali: Le nhlanganisela ingahle isetshenziswe njengengxenye ye-standard noma ireferensi ngezinjongo zokuhlaziya nokuthuthukiswa kwendlela kuma-laboratoratories okucwaninga.
2.Ucwaningo lwebhayoloji: lungasetshenziswa ezifundweni eziphenya iqhaza lemigqa kanye nezindlela zazo ezivela emikhondweni ehlukahlukene yomzimba noma ye-biochemical.
Uyacelwa uqaphele ukuthi izinhlelo zokusebenza kanye nokusetshenziswa kwe-2-amino-2- (4-chlorophenyl) acetic acid incike ekucwaningeni nasekuthuthukisweni. Hlala uthintana nezincwadi zesayensi njalo, izidingo zokulawula, kanye nochwepheshe abafanele ngaphambi kokusebenzisa noma ukucubungula ukusetshenziswa kwalo enkombeni ethile.
![3- [Tris- (hydroxymethyl) -Methyamino] -1-propasulfonic acid; Case No.: 29915-38-6](https://cdn.globalso.com/pengnuochemical/3-13-Dihydroxy-2-hydroxymethylpropan-2-ylazaniumylpropane-1-sulfonate-29915-38-6.png)