Imikhiqizo
I-6-Methyluracil 2,4-Dihydroxy-6-methylpyrimidine
Synonimes:6-methyluracil;6-methyluracil, 14C-ilebula;AWD 23-15;AWD-23-15;methacil;methyluracil;pseudothymine
Impahla Yekhemikhali ye-6-Methyluracil
● Ukubukeka/Umbala:okumhlophe kuya kokumhlophe okuqinile njengekristalu
● Umfutho Wokuhwamuka:1.16E-07mmHg ku-25°C
● Indawo Encibilika:318 °C (dec.)(lit.)
● I-Refractive Index: 1.489
● Indawo yokubilisa:420.4 °C ku-760 mmHg
● I-PKA:pK1:9.52 (25°C)
● Iphuzu Elikhanyayo:208 °C
● I-PSA: 65.72000
● Ukuminyana:1.226 g/cm3
● I-LogP:-0.62840
● Ukushisa Kwesitoreji.:Isimo esingenasici,Izinga lokushisa Legumbi
● Ukunyibilika.:DMSO (Kancane), i-Methanol (Kancane, Iyashisisa, I-Sonicated)
● Ukunyibilika kwamanzi.:7 g/L (22 ºC)
● XLogP3:-0.8
● Isibalo Somnikeli Webhondi Ye-Hydrogen:2
● Isibalo Sokwamukela Ibhondi Ye-Hydrogen:2
● I-Rotatable Bond Count:0
● IMisa Langempela:126.042927438
● Isibalo se-athomu esindayo:9
● Ukuba yinkimbinkimbi:195
Ubumsulwa/Ikhwalithi
99% *idatha evela kubahlinzeki abangavuthiwe
6-Methyluracil *idatha evela kubahlinzeki be-reagent
Ulwazi Oluphephile
● Ama-Pictogram:
Xn
● Amakhodi Wengozi:Xn
● Izitatimende:62-63
● Izitatimende Zokuphepha:36/37/39-45-36/37
Iwusizo
● I-Canonical SMILES: CC1=CC(=O)NC(=O)N1
● Ukusetshenziswa: I-6-Methyluracil (i-cas# 626-48-2) iyinhlanganisela ewusizo ku-organic synthesis.6-Methyluracil, eyaziwa nangokuthi i-thymine noma i-5-methyluracil, i-organic compound ene-chemical formula C5H6N2O2.Kuyi-pyrimidine derivative kanye nengxenye yama-nucleic acid.I-Thymine, kanye ne-adenine, i-cytosine, ne-guanine, ingenye yama-nucleobase amane atholakala ku-DNA. I-Thymine idlala indima ebalulekile ku-DNA ngokumatanisa ne-adenine ngokusebenzisa i-hydrogen bonding, yakhe enye yamabhangqa ayisisekelo akha i-double helix structure.Ngokuqondile, i-thymine yakha izibopho ezimbili ze-hydrogen ne-adenine ku-DNA.Ku-RNA, i-uracil ithatha indawo ye-thymine futhi yenza amapheya ayisisekelo ne-adenine.I-Thymine inesibopho sokuthwala ulwazi lofuzo ngaphakathi kwe-molecule ye-DNA.Isebenza njengepulani yokuhlanganiswa kwamaprotheni futhi idlala indima ebalulekile ekudluliseleni izici zofuzo kusuka kwesinye isizukulwane kuya kwesinye.Ngaphandle kwendima yayo ku-DNA ne-RNA, i-thymine iphinde isebenze njengenhloso ebalulekile emithini elwa nomdlavuza.Amanye ama-chemotherapeutic agents aqondise kuma-enzyme anesibopho sokwenza i-thymine, ngaleyo ndlela avimbele ukukhula kwamangqamuzana omdlavuza.I-Thymine iyatholakala ngezohwebo futhi isetshenziswa kabanzi ocwaningweni lwesayensi, ekusetshenzisweni kwezokwelapha, nasembonini yezemithi.Lapho uphatha i-thymine, kubalulekile ukulandela izimiso zokuphepha ezifanele zaselabhorethri, okuhlanganisa ukugqoka izinto zokuzivikela ezifanele nokusebenza endaweni enomoya omuhle.Ukwengeza, i-thymine kufanele igcinwe endaweni eyomile futhi epholile ukuvimbela ukuwohloka nokugcina ukuzinza kwayo.
