Imikhiqizo
I-4-Hydroxy-D-(-)-2-phenylglycine
Synonimes:(R,S) -3HPG;4-hydroxyphenylglycine;4-hydroxyphenylglycine hydrobromide, (+-)-isomer;4-hydroxyphenylglycine hydrochloride, (R) -isomer;4-hydroxyphenylglycine perchlorate, (+-)-isomer;4 -hydroxyphenylglycine, (+-)-isomer;4-hydroxyphenylglycine, (R) -isomer;4-hydroxyphenylglycine, (S) -isomer;4-hydroxyphenylglycine, 2,4-dimethylbenzenesulfonate, (+-) -isome;4-hydroxyphenylglycine , 2,4-dimethylbenzenesulfonate, (R) -isomer;4-hydroxyphenylglycine, 4-methylbenzenesulfonate, (+-)-isomer;4-hydroxyphenylglycine, 4-methylbenzenesulfonate, (S) -isomer;4-hydroxyphenylglycine, monosodium salt;4 -hydroxyphenylglycine, monosodium salt, (R) -isomer;Dp-hydroxyphenylglycine;L-4-hydroxyphenylglycine;oxfenicine;p-hydroxyphenylglycine;UK 25842;UK-25842
I-Chemical Property ye-D(-)-4-Hydroxyphenylglycine
● Ukubukeka/Umbala:impushana emhlophe
● Umfutho Wokuhwamuka:0.000272mmHg ku-25°C
● Indawo Encibilika:240 °C (dec.)(lit.)
● I-Refractive Index:-158 ° (C=1, 1mol/L HCl)
● Indawo yokubilisa:365.8 °C ku-760 mmHg
● I-PKA:2.15±0.10(Kubikezelwe)
● Iphuzu Elikhanyayo:175 °C
● I-PSA:83.55000
● Ukuminyana:1.396 g/cm3
● I-LogP:1.17690
● Ukushisa Kwesitoreji.: Gcina ngaphansi kuka-+30°C.
● Ukunyibilika.:5g/l
● Ukunyibilika kwamanzi.:5 g/L (20 ºC)
● XLogP3:-2.1
● Isibalo Somnikeli Webhondi Ye-Hydrogen:3
● Isibalo Sokwamukela Ibhondi Ye-Hydrogen:4
● Isibalo Sebhondi Eshintshayo:2
● IMisa Langempela:167.058243149
● Isibalo se-athomu esindayo:12
● Ukuba yinkimbinkimbi:164
Ubumsulwa/Ikhwalithi
99% *idatha evela kubahlinzeki abangavuthiwe
4-Hydroxy-D-(-)-2-phenylglycine *idatha evela kubahlinzeki be-reagent
Ulwazi Oluphephile
● Ama-Pictogram:
Xi
● Amakhodi Wengozi:Xi
● Izitatimende:36/37/38
● Izitatimende Zokuphepha:26-36-24/25
Iwusizo
● I-Canonical AMAMAMOMO: C1=CC(=CC=C1C(C(=O)O)N)O
● UKUMAMAtheka kwe-Isomeric: C1=CC(=CC=C1[C@H](C(=O)O)N)O
● Ukusetshenziswa: I-4-Hydroxy-D-(-)-2-phenylglycine iyinhlanganisela esetshenziswa kakhulu ekulungiseni okokwenziwa kwama-antibiotic e-β-lactam.I-4-Hydroxy-D-(-)-2-phenylglycine (Cefadroxil EP Impurity A(Amoxicillin EP Impurity A)) iyinhlanganisela esetshenziselwa ikakhulukazi ukulungiswa kokwenziwa kwama-antibiotic e-β-lactam.
I-4-Hydroxy-D-phenylglycine, eyaziwa nangokuthi i-4-hydroxy-D-phenylglycine noma i-4-HDPG, iyinhlanganisela yamakhemikhali ene-molecular formula C8H9NO3.I-amino acid derivative futhi iyingxenye yesigaba se-phenylglycines.4-Hydroxy-D-phenylglycine isetshenziswa ngokuyinhloko njengesakhiwo sokwakha ekuhlanganiseni kwamakhemikhali emithi.Isebenza njengempahla eluhlaza ekukhiqizeni ama-antibiotic athile, njenge-cefadroxil ne-cephradine.Lawa ma-antibiotics ayingxenye ye-cephalosporin futhi asetshenziselwa ukwelapha izifo ezibangelwa amagciwane.Ngaphezu kwendima yayo njengesandulela ekuhlanganiseni kwemithi, i-4-Hydroxy-D-phenylglycine nayo iye yaphenywa ngezindawo zayo zokwelapha ezingase zibe khona.Ucwaningo lubonisa ukuthi ingase ibe nemiphumela yokulwa ne-antioxidant ne-anti-inflammatory, engayenza ibe usizo ekuthuthukisweni kwemithi emisha yezimo ezihlukahlukene zezokwelapha.Sekukonke, i-4-Hydroxy-D-phenylglycine iyinhlanganisela yamakhemikhali enezinhlelo zokusebenza ezibalulekile ekuhlanganiseni kwemithi kanye namandla ukusetshenziswa kokwelapha.Indima yayo njengesivikelo sokwakha ekukhiqizeni ama-antibiotic igqamisa ukubaluleka kwayo embonini yezemithi.
