1,3-Propane sultone

Incazelo emfushane:

Igama Lomkhiqizo:1,3-Propane sultone

Omqondofana:I-3-HYDROXY-1-PROPANESULFONIC ACID I-GAMMA-SULTONE;3-HYDROXY-1-PROPANESULFONIC ACID SULTONE;3-HYDROXY-1-PROPANE SULFONIC SULTONE;3-HYDROXYPROPANESULFONIC-GAMPONIC-HYDROXYPROPANESULFONIC-GAMPONIC-3-HYDROXYPROPANESULFONIC-ACOLTONE I-ACID SULTONE;1,2- I-OXATHIOLANE, 2,2-DIOXIDE;1,3-PROPANESULTONE;PROPANE SULTONE

I-CAS:1120-71-4

MF:I-C3H6O3S

MW:122.14

I-EINECS:214-317-9

Izigaba zomkhiqizo:Sulfur & Selenium Compounds;Heterocyclic Compounds;Industrial/Fine Chemicals;Boron, Nitrile, Thio,&TM-Cpds;Heterocycles;Halogenated Heterocycles ,Quinuclidines;Pharmaceutical intermediates;1120-71-4

Ifayela le-Mol:1120-71-4.mol

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ipropane sultone Chemical Properties

Iphoyinti lokuncibilika	30-33 °C (okhanyisiwe)
Iphuzu elibilayo	180 °C/30 mmHg (okhanyisiwe)
ukuminyana	1.392 g/mL ku-25 °C (lit.)
umfutho womhwamuko	0.001-0.48Pa ku-20-25℃
inkomba ye-refractive	1.4332 (isilinganiso)
Fp	>230 °F
izinga lokushisa lokugcina.	Umkhathi ongenayo, izinga lokushisa legumbi
ifomu	impushana
umbala	Okumhlophe noma Okungenambala ukuya kokuphuzi Okukhanyayo
Ukuncibilika kwamanzi	Incibilika kancane
I-FreezingPoint	30.0 ukuze 33.0 ℃
Kuyazwela	Kuyazwela Umswakama
I-BRN	109782
Ukuzinza:	Izinzile, kodwa umswakama uyazwela.Akuhambisani nama-oxidizing agents aqinile, ama-acids aqinile, izisekelo eziqinile.
I-InChIKey	FSSPGSAQUIYDCN-UHFFFAOYSA-N
I-LogP	-2.86--0.28 at 20℃
Ireferensi ye-CAS Database	1120-71-4(CAS DataBase Reference)
I-NIST Chemistry Reference	1,2-Oxathiolane, 2,2-dioxide(1120-71-4)
I-IARC	2A (Vol. 4, Sup 7, 71, 110) 2017
I-EPA Substance Registry System	I-1,3-Propane sultone (1120-71-4)

Ulwazi Lokuphepha

Amakhodi Wengozi	T
Izitatimende Zobungozi	45-21/22
Izitatimende Zokuphepha	53-45-99
I-RIDADR	UN 2810 6.1/PG 3
I-WGK Germany	3
I-RTECS	RP5425000
F	21
I-TSCA	Yebo
I-HazardClass	6.1
PackingGroup	III
Ikhodi ye-HS	29349990
Idatha Yezinto Eziyingozi	1120-71-4(Idatha Yezinto Eziyingozi)

Ukusetshenziswa kwe-propane sultone kanye nokuhlanganiswa

Incazelo	I-propane sultone eyaziwa nangokuthi i-1,3-propane sultone yaqala ukukhiqizwa e-United States ngo-1963. I-propane sultone ikhona ezingeni lokushisa elivamile njengoketshezi olungenambala olunephunga elibi noma njengesiqinile esicwebezelayo esimhlophe.
Chemical Properties	I-1,3-Propane sultone iyikristalu eqinile emhlophe noma uketshezi olungenambala olungaphezu kuka-30°C.Ikhipha iphunga elibi njengoba incibilika.Incibilika kalula emanzini nasezincibilikisini eziningi eziphilayo njengama-ketone, ama-ester nama-hydrocarbon anephunga elimnandi.
Isebenzisa	I-1,3-Propane sultone isetshenziswa njengekhemikhali emaphakathi ukwethula iqembu le-sulfopropyl libe ngama-molecule futhi linikeze ukuncibilika kwamanzi kanye nohlamvu lwe-anionic kuma-molecule.Isetshenziswa njengekhemikhali emaphakathi ekukhiqizeni ama-fungicides, ama-insecticides, ama-cation-exchange resins, odayi, ama-vulcanization accelerators, okokuhlanza, ama-lathering agents, ama-bacteriostats, kanye nenhlobonhlobo yamanye amakhemikhali futhi njenge-corrosion inhibitor yensimbi emnene (engagxiliwe).
Isicelo	I-1,3-Propanesultone iyi-ester ye-cyclic sulfonic esetshenziselwa ukwethula ukusebenza kwe-propane sulfonic esakhiweni sezinto eziphilayo.Isetshenziswe ekulungiseleleni i-poly[2-ethynyl-N-(propylsulfonate)pyridinium betaine],novel poly(4-vinylpyridine) esekelwe i-acid ionic liquid catalyst,novel poly(4-vinylpyridine) esekelwa i-acid ionic liquid catalyst. I-1,3-Propanesultone ingasetshenziswa ukuhlanganisa: I-sulfonic acid esebenzayo esebenzayo i-ionic liquid modified silica catalyst engasetshenziswa ku-hydrolysis ye-cellulose. Usawoti oncibilikisiwe wohlobo lweZwitterionic anezakhiwo eziyingqayizivele ze-ion conductive. I-Zwitterionic organofunctional silicones nge-quaternization ye-organic amine functional silicones.
Ukulungiselela	I-1,3-propane sultone ikhiqizwa ukuthengisa ngokuqeda amanzi e-gamma-hydroxy-propanesulfonic acid, elungiswa nge-sodium hydroxypropanesulfonate.lo sawoti we-sodium ulungiswa ngokufaka i-sodium bisulfite ku-allil alcohol.
Incazelo	I-1,3-Propane sultone iyi-sultone.Isetshenziswa njenge-chemical medium.Lapho ishiselwa ukuze ibole, ikhipha intuthu enobuthi yama-sulphur oxides.Abantu bangase bachayeke ezinsalela ze-1,3-propane sultone lapho besebenzisa imikhiqizo ekhiqizwe kule nhlanganisela.Izindlela eziyinhloko zokuchayeka komuntu ku-1,3-propane sultone ukumunca nokuhogela.Ukuthintana naleli khemikhali kungabangela ukucasuka okuncane kwamehlo nesikhumba.Kulindeleke ngokunengqondo ukuthi ibe yi-carcinogen yomuntu.
Incazelo evamile	I-Propanesultone iyi-synthetic, uketshezi olungenambala noma okuqinile okucwebezelayo okumhlophe okuncibilika kalula emanzini kanye nezinyibilikisi eziningi eziphilayo njengama-ketone, ama-ester nama-hydrocarbon anephunga elimnandi.Iphuzu lokuncibilika lingu-86°F.Ikhulula iphunga elibi lapho incibilika.
Ukusabela Komoya Namanzi	Incibilika emanzini [Hawley].
Iphrofayela Yokuphinda Isebenze	I-1,3-Propanesultone isabela kancane namanzi ukuze inikeze i-3-hydroxopropanesulfonic acid.Lokhu kusabela kungase kusheshiswe yi-asidi.Ingase isabele ngezinciphisi ezinamandla ukuze inikeze i-hydrogen sulfide enobuthi nevuthayo.
Ingozi	I-carcinogen engenzeka.
Ingozi Yezempilo	I-Propane sultone iyi-carcinogen ezilwaneni zokuhlola kanye ne-carcinogen yomuntu okusolakala ukuthi.Ayikho idatha yomuntu etholakalayo.Iwumdlavuza kumagundane uma unikezwa ngomlomo, ngomthambo, noma ngokuchayeka ngaphambi kokubeletha kanye ne-carcinogen yasendaweni kumagundane namagundane lapho inikezwa ngaphansi kwesikhumba.
Ukuvutha nokugqama	Okungashi
Iphrofayela Yokuphepha	I-carcinogen eqinisekisiwe enedatha yokuhlola i-carcinogenic, i-neoplastigenic, i-tumorigenic, ne-teratogenic.Ubuthi ngomzila ongaphansi kwesikhumba.Inobuthi obumaphakathi ngokuthinta isikhumba nemizila ye-intraperitoneal.Kubikiwe idatha yokuguquguquka komuntu.Kufakwe njenge-carcinogen yobuchopho bomuntu.I-slun irritant.Uma ishiselwa ukuze ibole ikhipha intuthu enobuthi ye-SOx.
Okungase kube ukuchayeka	Ingozi engaba khona kulabo abathintekayo ekusetshenzisweni kwaleli khemikhali emaphakathi ukwethula iqembu le-sulfopropyl (-CH 2 CH 2 CH 2 SO 3-) kuma-molecule weminye imikhiqizo.
I-Carcinogenicity	I-1,3-Propane sultone ilindeleke ngokunengqondo ukuthi ibe i-carcinogen yomuntu ngokusekelwe ebufakazini obanele be-carcinogenicity kusukela ezifundweni zezilwane zokuhlola.
Isiphetho Sezemvelo	Imizila Nezindlela Nezakhiwo Ze-Physicochemical Efanelekayo Ukubukeka: I-crystalline emhlophe eqinile noma uketshezi olungenambala. Ukuncibilika: kuncibilika kalula kuma-ketone, ama-ester, nama-hydrocarbon anephunga elimnandi;engancibiliki kuma-aliphatic hydrocarbon;futhi inyibilika emanzini (100 gl^-1). Ukuziphatha Kokwahlukanisa Emanzini, Kwenhlabathi, Nasemhlabeni Uma i-1,3-propane sultone ikhishelwa enhlabathini, kuzolindeleka ukuthi i-hydrolyze ngokushesha uma inhlabathi inomswakama, ngokusekelwe ku-hydrolysis esheshayo ebonwa esixukwini esinamanzi.Njengoba ishintsha ngokushesha i-hydrolyzes, i-adsorption and volatilization kusuka enhlabathini emanzi akulindelekile ukuthi kube izinqubo ezibalulekile, nakuba kungekho datha eqondene ngqo nesiphetho se-1,3-propane sultone enhlabathini eyatholakala.Uma ikhishelwa emanzini, kuzolindeleka ukuthi i-hydrolyze ngokushesha.Umkhiqizo we-hydrolysis yi-3-hydroxy-1-propansulfonic acid.Njengoba i-hydrolyze ngokushesha, i-bioconcentration, i-volatilization, kanye ne-adsorption ku-sediment kanye nezinto eziqinile ezimisiwe akulindelekile ukuthi kube izinqubo ezibalulekile.Uma ikhishelwe emkhathini, izongenwa kalula yi-photooxidation ngokusabela kwesigaba somhwamuko ngama-hydroxyl radicals akhiqizwe ngezithombe ezinohhafu wempilo yezinsuku eziyi-8 ezilinganiselwe le nqubo.
Ukuthumela ngomkhumbi	UN2811 Okuqinile okunobuthi, i-organic, nos, Ikilasi Lengozi: 6.1;Amalebula: 6.1-Izinto ezinobuthi, Igama Lobuchwepheshe Liyadingeka.UN2810 Uketshezi olunobuthi, i-organic, nos, Ikilasi Lengozi: 6.1;Amalebula: 6.1-Izinto ezinobuthi, Igama Lobuchwepheshe Liyadingeka.
Ukuhlolwa kobuthi	Ukusabela kwe-propane sultone nge-guanosine kanye ne-DNA ku-pH 6-7.5 kunikeza i-N7-alkylguanosine njengomkhiqizo oyinhloko (>90%).Ubufakazi obufanayo buphakamisa ukuthi izithasiselo ezimbili ezincane kwakuyi-N1- kanye ne-N6-alkyl derivatives, ezibalelwa cishe ku-1.6 kanye no-0.5% wesamba se-adducts, ngokulandelanayo.I-N7- ne-N1-alkylguanine nazo zitholwe ku-DNA zasabela nge-propane sultone.
Ukungahambisani	Akuhambisani nama-oxidizers (i-chlorate, i-nitrate, i-peroxides, i-permanganate, i-perhlorates, i-chlorine, i-bromine, i-fluorine, njll.);ukuthintana kungase kubangele imililo noma ukuqhuma.Gcina kude nezinto ze-alkaline, izisekelo eziqinile, ama-asidi aqinile, ama-oxoacids, ama-epoxide.